GSK-3 beta(Phospho-Thr390) Rabbit Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) Members of this family play

Members of this family play a role in cytoskeletal regulation

This protein binds to all three of the tumor suppressor proteins pRB

but not glucocorticoid receptor

This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes

Positively regulates the beta-catenin pathway (canonical Wnt signaling pathway) and is required for MCC-mediated repression of the beta-catenin pathway (PubMed: 24824780)

GSK-3 beta(Phospho-Thr390) Rabbit Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) Members of this family playThe protein encoded by this gene is a serine threonine kinase belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism neuronal cell development and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants